Peptide Science, Explained

In-depth articles covering clinical research, peptide comparisons, sourcing guides, and the latest findings from peer-reviewed studies. Written for researchers and anyone tracking the evidence.

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Featured graphic for the peptides.fyi article "PT-141 (Bremelanotide): What the Clinical Research Shows" — abstract molecular and peptide-chain illustration.
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8
Minutes
Clinical Research

PT-141 (Bremelanotide): What the Clinical Research Shows

The only FDA-approved peptide for sexual desire. We break down the clinical trials behind PT-141, how it works through melanocortin receptors in the brain, and what the data says about…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Peptide Combinations: What the Research Shows" — abstract molecular and peptide-chain illustration.
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9
Minutes
Science & Mechanisms

Peptide Combinations: What the Research Shows

Some peptides work better together than alone. We look at the research behind popular combinations, the science of synergy, and what to watch out for when stacking compounds.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Tesamorelin: The FDA-Approved GHRH Analog for Visceral Fat" — abstract molecular and peptide-chain illustration.
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6
Minutes
Clinical Research

Tesamorelin: The FDA-Approved GHRH Analog for Visceral Fat

The only FDA-approved GHRH analog specifically shown to reduce visceral belly fat. We cover the clinical trial evidence, how it works differently from other GH peptides, and its safety record.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Growth Hormone Peptides Compared: CJC-1295, Ipamorelin & More" — abstract molecular and peptide-chain illustration.
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6
Minutes
Peptide Comparisons

Growth Hormone Peptides Compared: CJC-1295, Ipamorelin & More

Five growth hormone compounds, each with a different mechanism. We compare CJC-1295, Ipamorelin, GHRP-6, Tesamorelin, and MK-677 side by side on potency, side effects, and research status.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Peptides for Anti-Aging: What the Research Supports" — abstract molecular and peptide-chain illustration.
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8
Minutes
Clinical Research

Peptides for Anti-Aging: What the Research Supports

From telomere extension to skin repair, multiple peptides are being studied for anti-aging effects. We sort through the evidence and separate the promising leads from the hype.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "GHK-Cu: The Copper Peptide in Skin Regeneration" — abstract molecular and peptide-chain illustration.
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8
Minutes
Science & Mechanisms

GHK-Cu: The Copper Peptide in Skin Regeneration

A naturally occurring peptide that binds copper and shows up in wound healing, collagen production, and even hair growth research. We cover what makes GHK-Cu one of the most studied…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "AOD-9604: The Fat Loss Fragment of Growth Hormone" — abstract molecular and peptide-chain illustration.
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8
Minutes
Science & Mechanisms

AOD-9604: The Fat Loss Fragment of Growth Hormone

Scientists isolated the fat-burning segment of growth hormone and turned it into its own compound. We look at what the clinical and preclinical data actually shows about AOD-9604 for fat…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "MK-677 (Ibutamoren): Research, Results & Mechanisms" — abstract molecular and peptide-chain illustration.
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6
Minutes
Science & Mechanisms

MK-677 (Ibutamoren): Research, Results & Mechanisms

MK-677 is not a peptide but it acts like one, boosting growth hormone through the ghrelin receptor. We cover how it works, what the research shows for body composition, and…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "TB-500 vs BPC-157: Comparing Two Recovery Peptides" — abstract molecular and peptide-chain illustration.
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7
Minutes
Peptide Comparisons

TB-500 vs BPC-157: Comparing Two Recovery Peptides

Both are recovery peptides, but they work through completely different mechanisms. We compare TB-500 and BPC-157 on healing speed, tissue types, and what the animal studies show.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Semaglutide for Weight Loss: The STEP Trial Program" — abstract molecular and peptide-chain illustration.
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7
Minutes
Clinical Research

Semaglutide for Weight Loss: The STEP Trial Program

The STEP trial program put semaglutide through rigorous testing across different patient groups. Here is a breakdown of the weight loss results, side effects, and what happened after people stopped…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "CJC-1295 DAC vs Ipamorelin: Growth Hormone Comparison" — abstract molecular and peptide-chain illustration.
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7
Minutes
Peptide Comparisons

CJC-1295 DAC vs Ipamorelin: Growth Hormone Peptides

Two popular growth hormone peptides with very different release patterns. We compare how they stimulate GH, their half-lives, and what researchers have learned about using them.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "BPC-157: Research on the Body Protection Compound" — abstract molecular and peptide-chain illustration.
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9
Minutes
Clinical Research

BPC-157: Research on the Body Protection Compound

BPC-157 is one of the most studied recovery peptides in animal research. We cover what scientists have found about gut healing, tendon repair, and tissue protection.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Retatrutide: What the Clinical Trial Data Shows" — abstract molecular and peptide-chain illustration.
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6
Minutes
Clinical Research

Retatrutide: What the Clinical Trial Data Shows

A new peptide that hits three receptors instead of two. Early trial data suggests it could produce even more weight loss than tirzepatide. We look at what the Phase 2…

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "The Science Behind Tirzepatide’s Dual-Action Mechanism" — abstract molecular and peptide-chain illustration.
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8
Minutes
Science & Mechanisms

The Science Behind Tirzepatide’s Dual-Action Mechanism

Tirzepatide works on two gut hormone receptors at once, and that dual action is why it outperforms single-target drugs. We walk through the biology of how it works.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Tirzepatide for Type 2 Diabetes: The SURPASS Trials" — abstract molecular and peptide-chain illustration.
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8
Minutes
Clinical Research

Tirzepatide for Type 2 Diabetes: The SURPASS Trials

The SURPASS trials tested tirzepatide across thousands of diabetes patients. Here is what the data actually showed for blood sugar control, weight loss, and how it stacked up against insulin.

Mar 28, 2026 Read →
Featured graphic for the peptides.fyi article "Tirzepatide vs Semaglutide: Weight Loss Comparison" — abstract molecular and peptide-chain illustration.
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6
Minutes
Peptide Comparisons

Tirzepatide vs Semaglutide: Weight Loss Comparison

The two biggest weight loss drugs go head to head. We break down the clinical trial numbers, side effect profiles, and mechanisms to show where each one actually wins.

Mar 28, 2026 Read →
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